3BPW

Crystal Structure of P. falciparum Orotidine 5'-monophosphate Decarboxylase Complexed with XMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Orotidine 5'-phosphate decarboxylase	polymer	342	39899.5	2	UniProt (Q8T6J6) Pfam (PF00215) UniProt (by SIFTS) (Q8IJH3)	Plasmodium falciparum
2	C, F (A, B)	XANTHOSINE-5'-MONOPHOSPHATE	non-polymer		365.2	2	Chemie (XMP)
3	D (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
4	E (B)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5	G, H (A, B)	water	water		18.0	366	Chemie (HOH)

Sequence modifications

A, B: 1 - 323 (UniProt: Q8T6J6)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79798.9
Non-Polymers*	Number of molecules	4
	Total formula weight	931.5
All*	Total formula weight	80730.4

*Water molecules are not included.