3BP6
Crystal structure of the mouse PD-1 Mutant and PD-L2 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Programmed cell death protein 1 | polymer | 117 | 13218.8 | 1 | UniProt (Q02242) Pfam (PF07686) | Mus musculus (mouse) | Protein PD-1, mPD-1, CD279 antigen |
| 2 | B (B) | Programmed cell death 1 ligand 2 | polymer | 202 | 22797.1 | 1 | UniProt (Q9WUL5) Pfam (PF22705) | Mus musculus (mouse) | Programmed death ligand 2, PD-L2, PD-1-ligand 2, PDCD1 ligand 2, Butyrophilin B7-DC, B7-DC, CD273 antigen |
| 3 | C, D, E, F (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence modifications
A: 1 - 117 (UniProt: Q02242)
B: 20 - 220 (UniProt: Q9WUL5)
| PDB | External Database | Details |
|---|---|---|
| Ser 50 | Cys 83 | engineered mutation |
| Leu 99 | Ala 132 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36015.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 368.4 | |
| All* | Total formula weight | 36384.3 |
