3BO5
Crystal structure of methyltransferase domain of human Histone-lysine N-methyltransferase SETMAR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase SETMAR | polymer | 290 | 32298.8 | 1 | UniProt (Q53H47) Pfam (PF05033) Pfam (PF00856) | Homo sapiens (human) | SET domain and mariner transposase fusion gene-containing protein, Metnase, Hsmar1 [Includes: Histone-lysine N-methyltransferase, and Mariner transposase Hsmar1] |
| 2 | B, C, D, E (A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | G, H (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | I (A) | water | water | 18.0 | 304 | Chemie (HOH) |
Sequence modifications
A: 1 - 289 (UniProt: Q53H47)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ala 259 | Glu 260 | engineered mutation |
| Ser 260 | Asp 261 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32298.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 830.2 | |
| All* | Total formula weight | 33129.1 |
