3BO5
Crystal structure of methyltransferase domain of human Histone-lysine N-methyltransferase SETMAR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase SETMAR | polymer | 290 | 32298.8 | 1 | UniProt (Q53H47) Pfam (PF05033) Pfam (PF00856) | Homo sapiens (human) | SET domain and mariner transposase fusion gene-containing protein, Metnase, Hsmar1 [Includes: Histone-lysine N-methyltransferase, and Mariner transposase Hsmar1] |
| 2 | B, C, D, E (A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (13792) PubChem (177678424) PubChem (189149) PubChem (439155) PubChem (25210495) PubChem (21125603) PubChem (44361184) PubChem (25203782) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (57544532) PubChem (52224400) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (5284331) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (71170554) PubChem (13231890) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (164157219) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 4 | G, H (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 5 | I (A) | water | water | 18.0 | 304 | Chemie (HOH) |
Sequence modifications
A: 1 - 289 (UniProt: Q53H47)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ala 259 | Glu 260 | engineered mutation |
| Ser 260 | Asp 261 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32298.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 830.2 | |
| All* | Total formula weight | 33129.1 |
