3BLJ

Crystal structure of human poly(ADP-ribose) polymerase 15, catalytic fragment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Poly(ADP-ribose) polymerase 15	polymer	221	25439.5	2	UniProt (Q460N3) Pfam (PF00644) In PDB	Homo sapiens (human)	PARP-15, B-aggressive lymphoma protein 3
2	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
3	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	A, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5		water	water		18.0	288	Chemie (HOH)

Sequence modifications

A, B: 459 - 656 (UniProt: Q460N3)

PDB	External Database	Details
Met 436	-	expression tag
His 437	-	expression tag
His 438	-	expression tag
His 439	-	expression tag
His 440	-	expression tag
His 441	-	expression tag
His 442	-	expression tag
Ser 443	-	expression tag
Ser 444	-	expression tag
Gly 445	-	expression tag
Val 446	-	expression tag
Asp 447	-	expression tag
Leu 448	-	expression tag
Gly 449	-	expression tag
Thr 450	-	expression tag
Glu 451	-	expression tag
Asn 452	-	expression tag
Leu 453	-	expression tag
Tyr 454	-	expression tag
Phe 455	-	expression tag
Gln 456	-	expression tag
Ser 457	-	expression tag
Met 458	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50878.9
Non-Polymers*	Number of molecules	5
	Total formula weight	265.6
All*	Total formula weight	51144.5

*Water molecules are not included.