3BJF
Pyruvate kinase M2 is a phosphotyrosine binding protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate kinase isozymes M1/M2 | polymer | 518 | 56633.3 | 4 | UniProt (P14618) Pfam (PF00224) Pfam (PF02887) | Homo sapiens (human) | Pyruvate kinase muscle isozyme, Pyruvate kinase 2/3, Cytosolic thyroid hormone-binding protein, CTHBP, THBP1 |
| 2 | E, I, M, Q (A, B, C, D) | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) PubChem (718) PubChem (10267) PubChem (172313) PubChem (440117) PubChem (5702629) PubChem (12800340) PubChem (16219368) PubChem (24802138) PubChem (46937007) PubChem (445557) PubChem (92209487) PubChem (124383956) PubChem (124540446) PubChem (135053794) PubChem (89534552) PubChem (92209485) PubChem (92209486) PubChem (123134048) PubChem (124202619) PubChem (124427861) PubChem (124524513) PubChem (124604817) PubChem (130233858) PubChem (133126640) PubChem (135055131) PubChem (140434362) PubChem (146159004) PubChem (160510795) | |||
| 3 | F, J, N, R (A, B, C, D) | OXALATE ION | non-polymer | 88.0 | 4 | Chemie (OXL) PubChem (71081) | |||
| 4 | G, K, O, S (A, B, C, D) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) PubChem (813) | |||
| 5 | H, L, P, T (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 6 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 609 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 14 - 531 (UniProt: P14618)
| PDB | External Database | Details |
|---|---|---|
| Asn 379 | His 379 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 226533.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1966.2 | |
| All* | Total formula weight | 228499.2 |
