3BJF
Pyruvate kinase M2 is a phosphotyrosine binding protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate kinase isozymes M1/M2 | polymer | 518 | 56633.3 | 4 | UniProt (P14618) Pfam (PF00224) Pfam (PF02887) | Homo sapiens (human) | Pyruvate kinase muscle isozyme, Pyruvate kinase 2/3, Cytosolic thyroid hormone-binding protein, CTHBP, THBP1 |
| 2 | E, I, M, Q (A, B, C, D) | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) | |||
| 3 | F, J, N, R (A, B, C, D) | OXALATE ION | non-polymer | 88.0 | 4 | Chemie (OXL) | |||
| 4 | G, K, O, S (A, B, C, D) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 5 | H, L, P, T (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 609 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 14 - 531 (UniProt: P14618)
| PDB | External Database | Details |
|---|---|---|
| Asn 379 | His 379 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 226533.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1966.2 | |
| All* | Total formula weight | 228499.2 |
