3BHT
Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor meriolin 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Cell division protein kinase 2 | polymer | 300 | 34200.6 | 2 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (human) | p33 protein kinase, CDK2 |
| 2 | B, D (B, D) | Cyclin-A2 | polymer | 262 | 30018.6 | 2 | UniProt (P30274) Pfam (PF00134) Pfam (PF02984) | Bos taurus (cattle) | Cyclin-A |
| 3 | E, I (A, C) | 4-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine | non-polymer | 241.2 | 2 | Chemie (MFR) | |||
| 4 | F, J (B, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, H, K (B, D) | MONOTHIOGLYCEROL | non-polymer | 108.2 | 3 | Chemie (SGM) | |||
| 6 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 1078 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 128438.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 855.6 | |
| All* | Total formula weight | 129294.1 |
