3BHD

Crystal structure of human thiamine triphosphatase (THTPA)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Thiamine triphosphatase	polymer	234	26048.8	2	UniProt (Q9BU02) Pfam (PF01928) In PDB	Homo sapiens (human)	ThTPase
2	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	A	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	A, B	CITRIC ACID	non-polymer		192.1	3	Chemie (CIT)
5	B	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6	B	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
7		water	water		18.0	225	Chemie (HOH)

Sequence modifications

A, B: 1 - 215 (UniProt: Q9BU02)

PDB	External Database	Details
Mse -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	52097.6
Non-Polymers*	Number of molecules	12
	Total formula weight	1226.8
All*	Total formula weight	53324.4

*Water molecules are not included.