3BHD
Crystal structure of human thiamine triphosphatase (THTPA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thiamine triphosphatase | polymer | 234 | 26048.8 | 2 | UniProt (Q9BU02) Pfam (PF01928) | Homo sapiens (human) | ThTPase |
| 2 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | F, H, I (A, B) | CITRIC ACID | non-polymer | 192.1 | 3 | Chemie (CIT) | |||
| 5 | G (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | J, K, L, M, N (B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 7 | O, P (A, B) | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 215 (UniProt: Q9BU02)
| PDB | External Database | Details |
|---|---|---|
| Mse -18 | - | expression tag |
| Gly -17 | - | expression tag |
| Ser -16 | - | expression tag |
| Ser -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Val -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52097.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1226.8 | |
| All* | Total formula weight | 53324.4 |
