3BGZ
Human Pim-1 kinase in complex with diphenyl indole inhibitor VX3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Proto-oncogene serine/threonine-protein kinase Pim-1 | polymer | 333 | 37984.1 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (human) | |
2 | A | 2,3-diphenyl-1H-indole-7-carboxylic acid | non-polymer | 313.3 | 1 | Chemie (VX3) | |||
3 | water | water | 18.0 | 112 | Chemie (HOH) |
Sequence modifications
A: 1 - 313 (UniProt: P11309)
PDB | External Database | Details |
---|---|---|
Met -19 | - | expression tag |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 37984.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 313.3 | |
All* | Total formula weight | 38297.4 |