3BGD

Thiopurine S-Methyltransferase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Thiopurine S-methyltransferase	polymer	260	29796.1	2	UniProt (O55060) Pfam (PF05724)	Mus musculus (Mouse)	Thiopurine methyltransferase
2	C, F (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
3	D, E, G, H (A, B)	9H-purine-6-thiol	non-polymer		152.2	4	Chemie (PM6)
4	I, J (A, B)	water	water		18.0	307	Chemie (HOH)

Sequence modifications

A, B: 1 - 240 (UniProt: O55060)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59592.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1377.5
All*	Total formula weight	60969.7

*Water molecules are not included.