3BG5

Crystal Structure of Staphylococcus Aureus Pyruvate Carboxylase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Pyruvate carboxylase	polymer	1173	131168.2	4	UniProt (Q99UY8) Pfam (PF00289) Pfam (PF02786) Pfam (PF02785) Pfam (PF00682) Pfam (PF02436) Pfam (PF00364) UniProt (by SIFTS) (A0A0H3JRU9) In PDB	Staphylococcus aureus
2	A, B, C, D	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)
3	A, B, C, D	5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL	non-polymer		228.3	4	Chemie (BTI)
4	A, B, C, D	PYRUVIC ACID	non-polymer		88.1	4	Chemie (PYR)
5	A, C	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)

Sequence modifications

A, B, C, D: 34 - 1182 (UniProt: Q99UY8)

PDB	External Database	Details
Met 11	-	expression tag
Gly 12	-	expression tag
Ser 13	-	expression tag
Ser 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
Ser 21	-	expression tag
Ser 22	-	expression tag
Gly 23	-	expression tag
Leu 24	-	expression tag
Val 25	-	expression tag
Pro 26	-	expression tag
Arg 27	-	expression tag
Gly 28	-	expression tag
Ser 29	-	expression tag
His 30	-	expression tag
Met 31	-	expression tag
Ala 32	-	expression tag
Ser 33	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	524672.6
Non-Polymers*	Number of molecules	14
	Total formula weight	2499.6
All*	Total formula weight	527172.2

*Water molecules are not included.