3BEI
Crystal structure of the slow form of thrombin in a self_inhibited conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Prothrombin | polymer | 44 | 5151.7 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | COAGULATION FACTOR II |
| 2 | B (B) | Prothrombin | polymer | 259 | 29779.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | COAGULATION FACTOR II |
| 3 | C (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | D, E (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
B: 16 - 247 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Asn 102 | Asp 462 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34930.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 405.4 | |
| All* | Total formula weight | 35336.3 |
