3BEG
Crystal structure of SR protein kinase 1 complexed to its substrate ASF/SF2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase SRPK1 | polymer | 381 | 43381.8 | 1 | UniProt (Q96SB4) Pfam (PF00069) | Homo sapiens (human) | Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1, SFRS protein kinase 1 |
| 2 | B (B) | Splicing factor, arginine/serine-rich 1 | polymer | 115 | 13021.5 | 1 | UniProt (Q07955) Pfam (PF00076) | Homo sapiens (human) | pre-mRNA-splicing factor SF2, P33 subunit, Alternative-splicing factor 1, ASF-1 |
| 3 | C (A) | PHOSPHOSERINE | non-polymer | 185.1 | 1 | Chemie (SEP) | |||
| 4 | D (A) | ALANINE | non-polymer | 89.1 | 1 | Chemie (ALA) | |||
| 5 | E (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) |
Sequence modifications
A: 58 - 255 (UniProt: Q96SB4)
A: 474 - 655 (UniProt: Q96SB4)
| PDB | External Database | Details |
|---|---|---|
| Ala 473 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56403.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 780.4 | |
| All* | Total formula weight | 57183.7 |
