3BC4
I84V HIV-1 protease in complex with a pyrrolidine diester
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | protease | polymer | 99 | 10789.7 | 1 | UniProt (P03367) Pfam (PF00077) UniProt (by SIFTS) (P04587) | Human immunodeficiency virus type 1 (Viruses) | |
| 2 | B, C (A) | 2-aminoethyl naphthalen-1-ylacetate | non-polymer | 229.3 | 2 | Chemie (LLG) | |||
| 3 | D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | E (A) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A: 1 - 99 (UniProt: P03367)
| PDB | External Database | Details |
|---|---|---|
| Val 84 | Ile 584 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10789.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 536.7 | |
| All* | Total formula weight | 11326.4 |
