3BBT
crystal structure of the ErbB4 kinase in complex with lapatinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, D) | Receptor tyrosine-protein kinase erbB-4 | polymer | 328 | 37491.5 | 2 | UniProt (Q15303) Pfam (PF07714) | Homo sapiens (human) | p180erbB4, Tyrosine kinase-type cell surface receptor HER4 |
| 2 | C, D (B, D) | N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE | non-polymer | 581.1 | 2 | Chemie (FMM) | |||
| 3 | E, F (B, D) | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74982.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1162.1 | |
| All* | Total formula weight | 76145.0 |
