3BAD
Crystal structure of D70A/H93G mutant of Human acidic fibroblast growth factor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Heparin-binding growth factor 1 | polymer | 146 | 16561.6 | 2 | UniProt (P05230) Pfam (PF00167) In PDB | Homo sapiens (human) | HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta |
2 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
3 | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 140 (UniProt: P05230)
PDB | External Database | Details |
---|---|---|
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Ala 70 | Asp 85 | engineered mutation |
Gly 93 | His 108 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 33123.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 192.1 | |
All* | Total formula weight | 33315.4 |