3BA4

Crystal structure of L26D mutant of Human acidic fibroblast growth factor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heparin-binding growth factor 1	polymer	146	16688.7	2	UniProt (P05230) Pfam (PF00167)	Homo sapiens (human)	HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta
2	C, D (A)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	E, F, G (A, B)	FORMIC ACID	non-polymer		46.0	3	Chemie (FMT)
4	H, I (A, B)	water	water		18.0	221	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 0	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Asp 26	Leu 41	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33377.4
Non-Polymers*	Number of molecules	5
	Total formula weight	330.2
All*	Total formula weight	33707.6

*Water molecules are not included.