3B76
Crystal structure of the third PDZ domain of human ligand-of-numb protein-X (LNX1) in complex with the C-terminal peptide from the coxsackievirus and adenovirus receptor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | E3 ubiquitin-protein ligase LNX | polymer | 118 | 12824.5 | 2 | UniProt (Q8TBB1) Pfam (PF00595) In PDB | Homo sapiens (human) | Numb-binding protein 1, Ligand of Numb-protein X 1 |
2 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
3 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
4 | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A, B: 408 - 498 (UniProt: Q8TBB1)
PDB | External Database | Details |
---|---|---|
Met 385 | - | expression tag |
His 386 | - | expression tag |
His 387 | - | expression tag |
His 388 | - | expression tag |
His 389 | - | expression tag |
His 390 | - | expression tag |
His 391 | - | expression tag |
Ser 392 | - | expression tag |
Ser 393 | - | expression tag |
Gly 394 | - | expression tag |
Val 395 | - | expression tag |
Asp 396 | - | expression tag |
Leu 397 | - | expression tag |
Gly 398 | - | expression tag |
Thr 399 | - | expression tag |
Glu 400 | - | expression tag |
Asn 401 | - | expression tag |
Leu 402 | - | expression tag |
Tyr 403 | - | expression tag |
Phe 404 | - | expression tag |
Gln 405 | - | expression tag |
Ser 406 | - | expression tag |
Met 407 | - | expression tag |
Gly 499 | - | SEE REMARK 999 |
Ser 500 | - | SEE REMARK 999 |
Ile 501 | - | SEE REMARK 999 |
Val 502 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 25649.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 147.1 | |
All* | Total formula weight | 25796.1 |