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3B6Q

Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) Mutant T686A in Complex with Glutamate at 2.0 Resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AGlutamate receptor 2polymer26329191.71UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
In PDB
Rattus norvegicus (Norway rat)GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2
2ASULFATE IONnon-polymer96.11Chemie (SO4)
3AGLUTAMIC ACIDnon-polymer147.11Chemie (GLU)
4waterwater18.0151Chemie (HOH)
Sequence modifications
A: 392 - 506 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 390-expression tag
Ala 391-expression tag
A: 632 - 775 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 630-linker
Thr 631-linker
Ala 686Thr 707engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29191.7
Non-Polymers*Number of molecules2
Total formula weight243.2
All*Total formula weight29434.8
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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