3B6E
Crystal structure of human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interferon-induced helicase C domain-containing protein 1 | polymer | 216 | 24104.9 | 1 | UniProt (Q9BYX4) Pfam (PF04851) | Homo sapiens (human) | Interferon-induced with helicase C domain protein 1, Helicase with 2 CARD domains, Helicard, Melanoma differentiation-associated protein 5, MDA-5, RNA helicase-DEAD box protein 116, Murabutide down-regulated protein |
| 2 | B (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 3 | C (A) | water | water | 18.0 | 174 | Chemie (HOH) |
Sequence modifications
A: 277 - 490 (UniProt: Q9BYX4)
| PDB | External Database | Details |
|---|---|---|
| Ser 275 | - | expression tag |
| Met 276 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24104.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 23.0 | |
| All* | Total formula weight | 24127.9 |
