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3B4F

Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with twelve mammalian isoforms: kinetic and X-Ray crystallographic studies

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 2polymer26029289.11UniProt (P00918)
Pfam (PF00194)
Homo sapiens (human)Carbonic anhydrase II, Carbonate dehydratase II, CA-II, Carbonic anhydrase C
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
MERCURY (II) IONnon-polymer200.61Chemie (HG)
4D
(A)
2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamidenon-polymer330.41Chemie (TUO)
5E
(A)
waterwater18.0194Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29289.1
Non-Polymers*Number of molecules3
Total formula weight596.4
All*Total formula weight29885.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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