3B23
Crystal structure of thrombin-variegin complex: Insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thrombin light chain | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | alpha-thrombin, light chain |
| 2 | B (B) | Thrombin heavy chain | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | alpha-thrombin, heavy chain |
| 3 | C (C) | Variegin | polymer | 32 | 3611.8 | 1 | UniProt (P85800) | Amblyomma variegatum | |
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37488.6 | |
| All* | Total formula weight | 37488.6 |
