3AYE
Crystal structure of galectin-3 CRD domian complexed with lactose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Galectin-3 | polymer | 135 | 15409.7 | 2 | UniProt (P17931) Pfam (PF00337) | Homo sapiens (human) | Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen |
| 2 | C, D (C, D) | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 2 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | beta-lactose | ||
| 3 | E, F, G (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 358 | Chemie (HOH) |
Sequence modifications
A, B: 117 - 250 (UniProt: P17931)
| PDB | External Database | Details |
|---|---|---|
| Met 116 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30819.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 684.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 31792.1 |
