3AUQ
Crystal structure of the human vitamin D receptor ligand binding domain complexed with Yne-diene type analog of active 14-epi-2alpha-methyl-19-norvitamin D3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Vitamin D3 receptor | polymer | 263 | 29805.3 | 1 | UniProt (P11473) Pfam (PF00104) In PDB | Homo sapiens (human) | VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1 |
2 | A | (1R,2S,3R)-5-[2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methyl-heptan-2-yl]-7a-methyl-1,2,3,3a,6,7-hexahydroinden-4-yl]ethynyl]-2-methyl-cyclohex-4-ene-1,3-diol | non-polymer | 414.6 | 1 | Chemie (CA9) | |||
3 | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 118 - 164 (UniProt: P11473)
A: 216 - 427 (UniProt: P11473)
PDB | External Database | Details |
---|---|---|
Gly 114 | - | expression tag |
Ser 115 | - | expression tag |
His 116 | - | expression tag |
Met 117 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29805.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 414.6 | |
All* | Total formula weight | 30220.0 |