3AU4

Structure of the human myosin-X MyTH4-FERM cassette bound to its specific cargo, DCC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Myosin-X	polymer	555	63425.5	1	UniProt (Q9HD67) Pfam (PF00784) Pfam (PF21989) Pfam (PF00788) Pfam (PF00373) In PDB	Homo sapiens (human)	Unconventional myosin-10
2	B	Netrin receptor DCC	polymer	63	6723.3	1	UniProt (P43146) In PDB	Homo sapiens (human)	Colorectal cancer suppressor, Immunoglobulin superfamily DCC subclass member 1, Tumor suppressor protein DCC
3		water	water		18.0	243	Chemie (HOH)

Sequence modifications

A: 1486 - 2058 (UniProt: Q9HD67)

PDB	External Database	Details
Gly 1484	-	expression tag
Pro 1485	-	expression tag
Thr 1663	Ser 1663	SEE REMARK 999
-	Thr 1872	deletion
-	Pro 1873	deletion
-	Cys 1874	deletion
-	Glu 1875	deletion
-	Arg 1876	deletion
-	Leu 1877	deletion
-	Glu 1878	deletion
-	Lys 1879	deletion
-	Arg 1880	deletion
-	Arg 1881	deletion
-	Thr 1882	deletion
-	Ser 1883	deletion
-	Phe 1884	deletion
-	Leu 1885	deletion
-	Glu 1886	deletion
-	Gly 1887	deletion
-	Thr 1888	deletion
-	Leu 1889	deletion
-	Arg 1890	deletion
-	Arg 1891	deletion

B: 1390 - 1447 (UniProt: P43146)

PDB	External Database	Details
Gly 1385	-	expression tag
Pro 1386	-	expression tag
Gly 1387	-	expression tag
Tyr 1388	-	expression tag
Gln 1389	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70148.8
All*	Total formula weight	70148.8

*Water molecules are not included.