3ATW
Structure-Based Design, Synthesis, Evaluation of Peptide-mimetic SARS 3CL Protease Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3C-Like Proteinase | polymer | 306 | 33832.6 | 2 | UniProt (P0C6U8) Pfam (PF05409) | SARS coronavirus (SARS-CoV) | 3CL-PRO, 3CLp, nsp5 |
| 2 | C, D (C, D) | peptide ACE-THR-VAL-ALC-HIS-H | polymer | 5 | 519.7 | 2 | BIRD (PRD_000815) | ||
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 306 (UniProt: P0C6U8)
| PDB | External Database | Details |
|---|---|---|
| Ile 188 | Arg 3428 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 68704.5 | |
| All* | Total formula weight | 68704.5 |
