3APW

Crystal structure of the A variant of human alpha1-acid glycoprotein and disopyramide complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Alpha-1-acid glycoprotein 2	polymer	190	22691.3	2	UniProt (P19652) Pfam (PF00061) In PDB	Homo sapiens (human)	AGP 2, Orosomucoid-2, OMD 2
2	A, B	Disopyramide	non-polymer		339.5	2	Chemie (DP0)
3		water	water		18.0	74	Chemie (HOH)

Sequence modifications

A, B: 1 - 183 (UniProt: P19652)

PDB	External Database	Details
Met 0	-	expression tag
Arg 149	Cys 167	engineered mutation
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45382.6
Non-Polymers*	Number of molecules	2
	Total formula weight	678.9
All*	Total formula weight	46061.5

*Water molecules are not included.