3AP1

Crystal structure of human tyrosylprotein sulfotransferase-2 complexed with PAP and C4 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein-tyrosine sulfotransferase 2	polymer	337	37743.7	2	UniProt (O60704) Pfam (PF13469) In PDB	Homo sapiens (human)	Tyrosylprotein sulfotransferase 2, TPST-2
2	S, T	C4 peptide	polymer	9	1208.1	2
3	A, B	ADENOSINE-3'-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (A3P)
4	B	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	319	Chemie (HOH)

Sequence modifications

A, B: 43 - 359 (UniProt: O60704)

PDB	External Database	Details
Met 23	-	EXPRESSION TAG
Gly 24	-	EXPRESSION TAG
Ser 25	-	EXPRESSION TAG
Ser 26	-	EXPRESSION TAG
His 27	-	EXPRESSION TAG
His 28	-	EXPRESSION TAG
His 29	-	EXPRESSION TAG
His 30	-	EXPRESSION TAG
His 31	-	EXPRESSION TAG
His 32	-	EXPRESSION TAG
Ser 33	-	EXPRESSION TAG
Ser 34	-	EXPRESSION TAG
Gly 35	-	EXPRESSION TAG
Val 36	-	EXPRESSION TAG
Pro 37	-	EXPRESSION TAG
Arg 38	-	EXPRESSION TAG
Gly 39	-	EXPRESSION TAG
Ser 40	-	EXPRESSION TAG
His 41	-	EXPRESSION TAG
Met 42	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	77903.6
Non-Polymers*	Number of molecules	3
	Total formula weight	946.5
All*	Total formula weight	78850.1

*Water molecules are not included.