3AL4

Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus

Replaces:  3LYJ

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	Hemagglutinin	polymer	333	36989.7	6	UniProt (C3W5S1) Pfam (PF00509)	Influenza A virus
2	B, D, F, H, J... (B, D, F, H, J...)	Hemagglutinin	polymer	181	20757.0	6	UniProt (C3W5S1) Pfam (PF00509)	Influenza A virus
3	M, N, P, Q, S (M, N, P, Q, S)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	5	In PDB GlyTouCan (G42666HT)
4	O, R (O, R)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
5	AA, BA, CA, DA, EA... (F, G, K, L, A...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	16	Chemie (NAG)
6	JA, KA, LA, MA, NA... (A, B, C, D, E...)	water	water		18.0	317	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K: 7 - 333 (UniProt: C3W5S1)

PDB	External Database	Details
Ala 1	-	expression tag
Asp 2	-	expression tag
Leu 3	-	expression tag
Gly 4	-	expression tag
Ser 5	-	expression tag
Arg 6	-	expression tag

B, D, F, H, J, L: 1 - 176 (UniProt: C3W5S1)

PDB	External Database	Details
Arg 177	-	expression tag
Leu 178	-	expression tag
Val 179	-	expression tag
Pro 180	-	expression tag
Arg 181	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	346480.5
Branched	Number of molecules	7
	Total formula weight	3295.1
Non-Polymers*	Number of molecules	16
	Total formula weight	3539.3
All*	Total formula weight	353314.9

*Water molecules are not included.