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3AL3

Crystal Structure of TopBP1 BRCT7/8-BACH1 peptide complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA topoisomerase 2-binding protein 1polymer23526471.31UniProt (Q92547)
Pfam (PF00533)
Homo sapiens (human)DNA topoisomerase II-binding protein 1, DNA topoisomerase II-beta-binding protein 1, TopBP1
2B
(B)
Peptide of Fanconi anemia group J proteinpolymer101327.31UniProt (Q9BX63)Protein FANCJ, ATP-dependent RNA helicase BRIP1, BRCA1-interacting protein C-terminal helicase 1, BRCA1-interacting protein 1, BRCA1-associated C-terminal helicase 1
3C
(A)
FORMIC ACIDnon-polymer46.01Chemie (FMT)
4D, E
(A, B)
waterwater18.096Chemie (HOH)
Sequence modifications
A: 1264 - 1493 (UniProt: Q92547)
PDBExternal DatabaseDetails
Gly 1259-expression tag
Pro 1260-expression tag
Leu 1261-expression tag
Gly 1262-expression tag
Ser 1263-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27798.6
Non-Polymers*Number of molecules1
Total formula weight46.0
All*Total formula weight27844.6
*Water molecules are not included.

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PDB entries from 2025-07-02

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