3AH5
Crystal Structure of flavin dependent thymidylate synthase ThyX from helicobacter pylori complexed with FAD and dUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Thymidylate synthase thyX | polymer | 216 | 25178.7 | 6 | UniProt (O26061) Pfam (PF02511) | Helicobacter pylori (Campylobacter pylori) | TS, TSase |
| 2 | BA, G, L, O, T... (F, A, B, C, D...) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 6 | Chemie (UMP) | |||
| 3 | AA, H, M, N, S... (F, A, B, C, D...) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 6 | Chemie (FAD) | |||
| 4 | CA, I, J, K, P... (F, A, C, D, E) | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
| 5 | DA, EA, FA, GA, HA... (A, B, C, D, E...) | water | water | 18.0 | 538 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 24 - 231 (UniProt: O26061)
| PDB | External Database | Details |
|---|---|---|
| Leu 232 | - | expression tag |
| Glu 233 | - | expression tag |
| His 234 | - | expression tag |
| His 235 | - | expression tag |
| His 236 | - | expression tag |
| His 237 | - | expression tag |
| His 238 | - | expression tag |
| His 239 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 151072.2 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 7619.1 | |
| All* | Total formula weight | 158691.3 |
