3AH5

Crystal Structure of flavin dependent thymidylate synthase ThyX from helicobacter pylori complexed with FAD and dUMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Thymidylate synthase thyX	polymer	216	25178.7	6	UniProt (O26061) Pfam (PF02511) In PDB	Helicobacter pylori (Campylobacter pylori)	TS, TSase
2	F, A, B, C, D...	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	6	Chemie (UMP)
3	F, A, B, C, D...	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	6	Chemie (FAD)
4	F, A, C, D, E	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
5		water	water		18.0	538	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 24 - 231 (UniProt: O26061)

PDB	External Database	Details
Leu 232	-	expression tag
Glu 233	-	expression tag
His 234	-	expression tag
His 235	-	expression tag
His 236	-	expression tag
His 237	-	expression tag
His 238	-	expression tag
His 239	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	151072.2
Non-Polymers*	Number of molecules	23
	Total formula weight	7619.1
All*	Total formula weight	158691.3

*Water molecules are not included.