3AEN
Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 containing Michaelis complex and alpha-amino-alpha, beta-butenoic acid-pyridoxal-5'-phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Methionine gamma-lyase | polymer | 389 | 42578.9 | 2 | UniProt (Q86D28) Pfam (PF01053) | Entamoeba histolytica | |
| 2 | B, D (B, D) | Methionine gamma-lyase | polymer | 389 | 42350.8 | 2 | UniProt (Q86D28) Pfam (PF01053) | Entamoeba histolytica | |
| 3 | E (A) | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) | |||
| 4 | F, I, J, K, N (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | G, L (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | H, M (B, D) | (2E)-2-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}but-2-enoic acid | non-polymer | 330.2 | 2 | Chemie (4LM) | |||
| 7 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 874 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 389 (UniProt: Q86D28)
B, D: 501 - 889 (UniProt: Q86D28)
| PDB | External Database | Details |
|---|---|---|
| Leu 308 | Ser 308 | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Leu 808 | Ser 308 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 169859.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1474.2 | |
| All* | Total formula weight | 171333.5 |
