3AEL
Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 containing methionine imine-pyridoxamine-5'-phosphate and alpha-amino-alpha, beta-butenoic acid-pyridoxal-5'-phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Methionine gamma-lyase | polymer | 389 | 42350.8 | 4 | UniProt (Q86D28) Pfam (PF01053) | Entamoeba histolytica | |
| 2 | E (A) | (2E)-2-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}but-2-enoic acid | non-polymer | 330.2 | 1 | Chemie (4LM) | |||
| 3 | F (A) | METHANETHIOL | non-polymer | 48.1 | 1 | Chemie (MEE) | |||
| 4 | G, J, L, O (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | H, M (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | I, K, N (B, C, D) | (2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-4-(methylsulfanyl)butanoic acid | non-polymer | 378.3 | 3 | Chemie (2LM) | |||
| 7 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 927 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 389 (UniProt: Q86D28)
| PDB | External Database | Details |
|---|---|---|
| Leu 308 | Ser 308 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 169403.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2081.8 | |
| All* | Total formula weight | 171484.9 |
