3A8Y
Crystal structure of the complex between the BAG5 BD5 and Hsp70 NBD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Heat shock 70 kDa protein 1 | polymer | 392 | 43150.8 | 2 | UniProt (P08107) Pfam (PF00012) UniProt (by SIFTS) (P0DMV8) | Homo sapiens (human) | HSP70.1, HSP70-1/HSP70-2 |
| 2 | C, D (C, D) | BAG family molecular chaperone regulator 5 | polymer | 142 | 16170.3 | 2 | UniProt (Q9UL15) Pfam (PF02179) | Homo sapiens (human) | BAG-5, Bcl-2-associated athanogene 5 |
| 3 | E, F (A, B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 522 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 388 (UniProt: P08107)
C, D: 341 - 447 (UniProt: Q9UL15)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Thr 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 334 | - | expression tag |
| Ser 335 | - | expression tag |
| Ser 336 | - | expression tag |
| Gly 337 | - | expression tag |
| Ser 338 | - | expression tag |
| Ser 339 | - | expression tag |
| Gly 340 | - | expression tag |
| Cys 448 | - | expression tag |
| Lys 449 | - | expression tag |
| Ala 450 | - | expression tag |
| Ala 451 | - | expression tag |
| Arg 452 | - | expression tag |
| Lys 453 | - | expression tag |
| Gln 454 | - | expression tag |
| Ala 455 | - | expression tag |
| Val 456 | - | expression tag |
| Arg 457 | - | expression tag |
| Leu 458 | - | expression tag |
| Ala 459 | - | expression tag |
| Gln 460 | - | expression tag |
| Asn 461 | - | expression tag |
| Ile 462 | - | expression tag |
| Leu 463 | - | expression tag |
| Ser 464 | - | expression tag |
| Tyr 465 | - | expression tag |
| Leu 466 | - | expression tag |
| Asp 467 | - | expression tag |
| Leu 468 | - | expression tag |
| Lys 469 | - | expression tag |
| Ser 470 | - | expression tag |
| Asp 471 | - | expression tag |
| Glu 472 | - | expression tag |
| Trp 473 | - | expression tag |
| Glu 474 | - | expression tag |
| Tyr 475 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 118642.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 244.3 | |
| All* | Total formula weight | 118886.4 |
