3A8W
Crystal Structure of PKCiota kinase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein kinase C iota type | polymer | 345 | 39854.8 | 2 | UniProt (P41743) Pfam (PF00069) Pfam (PF00433) | Homo sapiens (human) | nPKC-iota, Atypical protein kinase C-lambda/iota, aPKC-lambda/iota, PRKC-lambda/iota |
| 2 | C, D (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 3 | E (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 162 | Chemie (HOH) |
Sequence modifications
A, B: 240 - 579 (UniProt: P41743)
| PDB | External Database | Details |
|---|---|---|
| Gly 235 | - | expression tag |
| Ala 236 | - | expression tag |
| Met 237 | - | expression tag |
| Asp 238 | - | expression tag |
| Pro 239 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79709.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1110.4 | |
| All* | Total formula weight | 80820.1 |
