3A7C
Crystal structure of TLR2-PE-DTPA complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Toll-like receptor 2, Variable lymphocyte receptor B | polymer | 580 | 65535.3 | 1 | UniProt (Q9QUN7) UniProt (Q4G1L2) Pfam (PF13516) Pfam (PF13855) Pfam (PF11921) In PDB | Mus musculus (mouse Inshore hagfish) | TLR2, VLRB.61 |
| 2 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | A | (10S,13R)-3-{2-[{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]ethyl}-10-hydroxy-5,16-dioxo-13-(tetradecanoyloxy)-9,11,15-trioxa-3,6-diaza-10-phosphanonacosan-1-oic acid 10-oxide | non-polymer | 1011.2 | 1 | Chemie (PDK) | |||
| 6 | A | LUTETIUM (III) ION | non-polymer | 175.0 | 1 | Chemie (LU) | |||
| 7 | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A: 1 - 506 (UniProt: Q9QUN7)
A: 509 - 576 (UniProt: Q4G1L2)
A: 509 - 576 (UniProt: Q4G1L2)
| PDB | External Database | Details |
|---|---|---|
| Ala 507 | - | linker |
| Ser 508 | - | linker |
| Leu 577 | - | expression tag |
| Val 578 | - | expression tag |
| Pro 579 | - | expression tag |
| Arg 580 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 65535.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1010.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1407.4 | |
| All* | Total formula weight | 67953.6 |
