3A5L
Crystal Structure of a Dictyostelium P109A Mg2+-Actin in Complex with Human Gelsolin Segment 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | S | Gelsolin | polymer | 127 | 14205.0 | 1 | UniProt (P06396) Pfam (PF00626) In PDB | Homo sapiens (human) | Actin-depolymerizing factor, ADF, Brevin, AGEL |
2 | C | Major actin | polymer | 375 | 41432.2 | 1 | UniProt (P07830) Pfam (PF00022) In PDB | Dictyostelium discoideum (Slime mold) | Actin-1, Actin-2, Actin-2-sub 1, Actin-4, Actin-5, Actin-6, Actin-7, Actin-8, Actin A8, Actin-IEL1, Actin-9, Actin-11, Actin-12, Actin A12, Actin-13, Actin-14, Actin-15, Actin A1, Actin III, Actin-3a, Actin-16, Actin M6, Actin-19, Actin-20, Actin-21 |
3 | S | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
4 | C | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
5 | C | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
6 | water | water | 18.0 | 293 | Chemie (HOH) |
Sequence modifications
S: 4 - 127 (UniProt: P06396)
C: 1 - 375 (UniProt: P07830)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Gly 2 | - | expression tag |
Ser 3 | - | expression tag |
Cys 35 | Asn 84 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ala 109 | Pro 110 | engineered mutation |
Ala 205 | Glu 206 | engineered mutation |
Ala 206 | Arg 207 | engineered mutation |
Ala 207 | Glu 208 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 55637.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 531.7 | |
All* | Total formula weight | 56168.9 |