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3KS9

Metabotropic glutamate receptor mGluR1 complexed with LY341495 antagonist

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Metabotropic glutamate receptor 1polymer49655689.12UniProt (Q13255)
Pfam (PF01094)
Homo sapiens (human)mGluR1
2C, G
(A, B)
2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alaninenon-polymer353.42Chemie (Z99)
3D, H
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
4E, F
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
5I, J
(A, B)
waterwater18.0651Chemie (HOH)
Sequence modifications
A, B: 28 - 518 (UniProt: Q13255)
PDBExternal DatabaseDetails
Ser 254Cys 254engineered mutation
Leu 519-expression tag
Val 520-expression tag
Pro 521-expression tag
Arg 522-expression tag
Gly 523-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight111378.3
Non-Polymers*Number of molecules6
Total formula weight1197.8
All*Total formula weight112576.1
*Water molecules are not included.

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PDB entries from 2025-10-08

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