38WY

Crystal structure of the CFTR inhibitory factor Cif with the S179A mutation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	CFTR inhibitory factor	polymer	295	33319.8	4	UniProt (A0A0H2ZD27)	Pseudomonas aeruginosa UCBPP-PA14	Cif,Cystic fibrosis transmembrane conductance regulator inhibitory factor,Epoxide hydrolase virulence factor,Toxin Cif
2	E, F, G, H, J (A, B, C)	CALCIUM ION	non-polymer		40.1	5	Chemie (CA) PubChem (271)
3	I, K (B, D)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT) PubChem (175)
4	L, M, N, O (A, B, C, D)	water	water		18.0	1327	Chemie (HOH)

Sequence modifications

A, B, C, D: 25 - 319 (UniProt: A0A0H2ZD27)

PDB	External Database	Details
Ala 179	Ser 179	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	133279.3
Non-Polymers*	Number of molecules	7
	Total formula weight	318.5
All*	Total formula weight	133597.8

*Water molecules are not included.