38LZ
Crystal structure of SARS-CoV-2 (Covid-19) Nsp3 macrodomain in complex with compound 12p
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Non-structural protein 3 | polymer | 170 | 18275.8 | 2 | UniProt (P0DTD1) Pfam (PF01661) | Severe acute respiratory syndrome coronavirus 2 | nsp3, PL2-PRO, Papain-like protease, Papain-like proteinase, PL-PRO |
| 2 | C, D (A, B) | N-{2-[({(3aR,4R,6R,6aR)-6-[(8R)-4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl]-6-cyano-2,2-dimethyltetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl}methyl)amino]-2-oxoethyl}-5-(4-fluorobenzene-1-sulfonamido)pyridine-3-carboxamide | non-polymer | 665.7 | 2 | Chemie (A1D4K) | |||
| 3 | E (B) | 3,6,9,12,15,18,21,24,27,30-decaoxadotriacontane-1,32-diol | non-polymer | 502.6 | 1 | Chemie (A1D4L) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 309 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 170 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36551.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1833.9 | |
| All* | Total formula weight | 38385.4 |
