38KZ

Cryo EM structure of GTP cyclohydrolase 1 (FolE) from Mycobacterium tuberculosis in complex with 8-oxo GTP

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	GTP cyclohydrolase 1	polymer	223	24717.2	10	UniProt (P9WN57)	Mycobacterium tuberculosis H37Rv	GTP cyclohydrolase I,GTP-CH-I
2	AA, CA, K, L, O... (I, J, A, B, C...)	ZINC ION	non-polymer		65.4	10	Chemie (ZN) PubChem (32051)
3	BA, DA, M, N, P... (I, J, B, C, D...)	8-OXO-GUANOSINE-5'-TRIPHOSPHATE	non-polymer		539.2	10	Chemie (8GT)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: 1 - 202 (UniProt: P9WN57)

PDB	External Database	Details
Met -20	-	initiating methionine
Ala -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Met -12	-	expression tag
Gly -11	-	expression tag
Thr -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Ala -7	-	expression tag
Gln -6	-	expression tag
Thr -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	247172.5
Non-Polymers*	Number of molecules	20
	Total formula weight	6045.9
All*	Total formula weight	253218.3

*Water molecules are not included.