37ZR
Crystal structure of TP53 (89-293, Y220C) bound to compound 3
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | Cellular tumor antigen p53 | polymer | 206 | 23083.3 | 2 | UniProt (P04637) | Homo sapiens (human) | Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53 |
| 2 | C, E (AAA, BBB) | 3-methoxy-N-(2-methoxyethyl)-N-methyl-4-[(3-{4-[(oxan-4-yl)amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl}prop-2-yn-1-yl)amino]benzene-1-sulfonamide | non-polymer | 608.7 | 2 | Chemie (A1DRM) | |||
| 3 | D, F (AAA, BBB) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) | |||
| 4 | G, H (AAA, BBB) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 89 - 293 (UniProt: P04637)
| PDB | External Database | Details |
|---|---|---|
| Gly 88 | - | expression tag |
| Cys 220 | Tyr 220 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46166.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1348.2 | |
| All* | Total formula weight | 47514.7 |
