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37PY

Human beta-cardiac myosin S1 motor domain with the essential light chain in the pre-powerstroke state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Myosin-7,Green fluorescent proteinpolymer1109126485.51UniProt (P12883)
UniProt (P42212)
Homo sapiens (human)Myosin heavy chain 7,Myosin heavy chain slow isoform,MyHC-slow,Myosin heavy chain,cardiac muscle beta isoform,MyHC-beta
2B
(B)
Myosin light chain 1/3, skeletal muscle isoformpolymer18820620.51UniProt (P05977)Mus musculus (house mouse)MLC1/MLC3,MLC1F/MLC3F,Myosin light chain alkali 1/2,Myosin light chain A1/A2
3C
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
4D
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
PubChem (1061)
5E
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
Sequence modifications
A: 1 - 842 (UniProt: P12883)
PDBExternal DatabaseDetails
Gly 843-linker
Ser 844-linker
Gly 845-linker
Lys 846-linker
Leu 847-linker
Gly 848-linker
Val 849-linker
A: 850 - 1086 (UniProt: P42212)
PDBExternal DatabaseDetails
Leu 912Phe 64conflict
Thr 913Ser 65conflict
Leu 1079His 231conflict
Gly 1087-expression tag
Leu 1088-expression tag
Asn 1089-expression tag
Asp 1090-expression tag
Ile 1091-expression tag
Phe 1092-expression tag
Glu 1093-expression tag
Ala 1094-expression tag
Gln 1095-expression tag
Lys 1096-expression tag
Ile 1097-expression tag
Glu 1098-expression tag
Trp 1099-expression tag
His 1100-expression tag
Glu 1101-expression tag
Asp 1102-expression tag
Tyr 1103-expression tag
Lys 1104-expression tag
Asp 1105-expression tag
Asp 1106-expression tag
Asp 1107-expression tag
Asp 1108-expression tag
Lys 1109-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight147106.0
Non-Polymers*Number of molecules3
Total formula weight546.5
All*Total formula weight147652.5
*Water molecules are not included.

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PDB entries from 2026-11-04

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