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37OC

PLK4-T170D (inactive) in complex with Cpd15

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase PLK4polymer27831723.71UniProt (O00444)Homo sapiens (human)Polo-like kinase 4,PLK-4,Serine/threonine-protein kinase 18,Serine/threonine-protein kinase Sak
2B
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
PubChem (1061)
3C
(A)
(7R)-N-{3-[1-(2-fluoro-2-methylpropyl)-1H-pyrazolo[4,3-c]pyridin-6-yl]-1H-pyrazol-4-yl}-7-hydroxy-7-(trifluoromethyl)-4-azaspiro[2.5]octane-4-carboxamidenon-polymer495.51Chemie (A1DQE)
4D
(A)
waterwater18.095Chemie (HOH)
Sequence modifications
A: 2 - 275 (UniProt: O00444)
PDBExternal DatabaseDetails
Ser 0-expression tag
Leu 1-expression tag
Glu 276-expression tag
Gly 277-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31723.7
Non-Polymers*Number of molecules2
Total formula weight590.4
All*Total formula weight32314.1
*Water molecules are not included.

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PDB entries from 2026-11-04

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