37OBEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase PLK4 | polymer | 278 | 31723.7 | 1 | UniProt (O00444) | Homo sapiens (human) | Polo-like kinase 4,PLK-4,Serine/threonine-protein kinase 18,Serine/threonine-protein kinase Sak |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | (7R)-N-(3-{1-(2-fluoro-2-methylpropyl)-3-[3-(trifluoromethyl)azetidin-1-yl]-1H-pyrazolo[4,3-c]pyridin-6-yl}-1H-pyrazol-4-yl)-7-hydroxy-7-(trifluoromethyl)-4-azaspiro[2.5]octane-4-carboxamide | non-polymer | 618.5 | 1 | Chemie (A1DQD) | |||
| 4 | D (A) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
A: 2 - 275 (UniProt: O00444)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Leu 1 | - | expression tag |
| Glu 276 | - | expression tag |
| Gly 277 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31723.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 714.6 | |
| All* | Total formula weight | 32438.3 |
