37NT

Crystal structure of the extracellular region of the human receptor tyrosine kinase MERTK

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tyrosine-protein kinase Mer	polymer	490	53565.7	1	UniProt (Q12866) Pfam (PF00047) Pfam (PF13927) Pfam (PF00041)	Homo sapiens (human)	Proto-oncogene c-Mer,Receptor tyrosine kinase MerTK
2	B, C, E (B, C, E)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	3	In PDB GlyTouCan (G15407YE)
3	D, F, G (D, F, G)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	3	In PDB GlyTouCan (G22768VO)
4	H, I (H, I)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
5	J (J)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
6	K (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG) PubChem (24139)

Sequence modifications

A: 1 - 484 (UniProt: Q12866)

PDB	External Database	Details
His 485	-	expression tag
His 486	-	expression tag
His 487	-	expression tag
His 488	-	expression tag
His 489	-	expression tag
His 490	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	53565.7
Branched	Number of molecules	9
	Total formula weight	6089.6
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	59876.5

*Water molecules are not included.