37FK
Cryo-EM structure of the human mitochondrial transcription initiation complex on HSP with TFAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-directed RNA polymerase, mitochondrial | polymer | 1230 | 138818.2 | 1 | UniProt (O00411) | Homo sapiens (human) | MtRPOL |
| 2 | B (B) | Dimethyladenosine transferase 2, mitochondrial | polymer | 396 | 45416.8 | 1 | UniProt (Q9H5Q4) | Homo sapiens (human) | Hepatitis C virus NS5A-transactivated protein 5,HCV NS5A-transactivated protein 5,Mitochondrial 12S rRNA dimethylase 2,Mitochondrial transcription factor B2,h-mtTFB,h-mtTFB2,hTFB2M,mtTFB2,S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase 2 |
| 3 | C (C) | Transcription factor A, mitochondrial | polymer | 246 | 29151.7 | 1 | UniProt (Q00059) | Homo sapiens (human) | mtTFA,Mitochondrial transcription factor 1,MtTF1,Transcription factor 6,TCF-6,Transcription factor 6-like 2 |
| 4 | D (D) | Non-template strand derived from the HSP | polymer | 71 | 21335.7 | 1 | GenBank (3057008929) | Homo sapiens | |
| 5 | E (E) | Template strand derived from the HSP | polymer | 71 | 22448.2 | 1 | GenBank (3057008929) | Homo sapiens |
Sequence modifications
D: 1 - 56 (GenBank: 3057008929)
| PDB | External Database | Details |
|---|---|---|
| Dt 57 | - | expression tag |
| Dt 58 | - | expression tag |
| Da 59 | - | expression tag |
| Dt 60 | - | expression tag |
| Dc 61 | - | expression tag |
| Dc 62 | - | expression tag |
| Dc 63 | - | expression tag |
| Dg 64 | - | expression tag |
| Da 65 | - | expression tag |
| Dc 66 | - | expression tag |
| Da 67 | - | expression tag |
| Dc 68 | - | expression tag |
| Dc 69 | - | expression tag |
| Dc 70 | - | expression tag |
| Dc 71 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 257170.7 | |
| All* | Total formula weight | 257170.7 |
