37EQ
Crystal Structure of Histone-lysine N-methyltransferase from Leishmania major in complex with 5'-O-(glycylsulfamoyl)adenosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase, H3 lysine-79 specific | polymer | 258 | 29630.0 | 1 | UniProt (Q4QIU2) Pfam (PF08123) | Leishmania major strain Friedlin | Histone H3-K76 methyltransferase,Histone H3-K79 methyltransferase,Histone-lysine N-methyltransferase,H3 lysine-76 specific |
| 2 | B (A) | 5'-O-(glycylsulfamoyl)adenosine | non-polymer | 403.4 | 1 | Chemie (G5A) PubChem (9909127) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) PubChem (32051) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 5 | E (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 50 - 299 (UniProt: Q4QIU2)
| PDB | External Database | Details |
|---|---|---|
| Met 42 | - | initiating methionine |
| Ala 43 | - | expression tag |
| His 44 | - | expression tag |
| His 45 | - | expression tag |
| His 46 | - | expression tag |
| His 47 | - | expression tag |
| His 48 | - | expression tag |
| His 49 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29630.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 504.2 | |
| All* | Total formula weight | 30134.3 |
