36XS
Structure of MBD4 R512K/D560N on a T:G Mispair
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methyl-CpG-binding domain protein 4 | polymer | 155 | 18498.4 | 1 | UniProt (O95243) | Homo sapiens (human) | Methyl-CpG-binding endonuclease 1,Methyl-CpG-binding protein MBD4,Mismatch-specific DNA N-glycosylase |
| 2 | B (B) | DNA (5'-D(*GP*CP*TP*GP*CP*GP*CP*GP*CP*TP*GP*G)-3') | polymer | 12 | 3695.4 | 1 | synthetic construct | ||
| 3 | C (C) | DNA (5'-D(*CP*CP*AP*GP*CP*GP*TP*GP*CP*AP*GP*C)-3') | polymer | 12 | 3648.4 | 1 | synthetic construct | ||
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 426 - 580 (UniProt: O95243)
| PDB | External Database | Details |
|---|---|---|
| Lys 512 | Arg 512 | conflict |
| Asn 560 | Asp 560 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 25842.2 | |
| All* | Total formula weight | 25842.2 |
