36XF

Cryo-EM structure of SLC6A19-ACE2 complex with CB3

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Sodium-dependent neutral amino acid transporter B(0)AT1	polymer	606	68115.8	2	UniProt (Q695T7)	Homo sapiens (human)	Solute carrier family 6 member 19,System B(0) neutral amino acid transporter AT1
2	B, D (B, D)	Angiotensin-converting enzyme 2	polymer	827	95042.3	2	UniProt (Q9BYF1)	Homo sapiens (human)	Angiotensin-converting enzyme homolog,ACEH,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15
3	E, F, G, H, I... (I, S, U, X, b...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	10	In PDB GlyTouCan (G42666HT)
4	O, P, R, S, T... (A, B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG) PubChem (24139)
5	Q, W (A, C)	N-[4-chloro-2-(trifluoromethyl)phenyl]-5-methyl-1,2-oxazole-3-carboxamide	non-polymer		304.7	2	Chemie (A1DLX)

Sequence modifications

B, D: -12 - 814 (UniProt: Q9BYF1)

PDB	External Database	Details
Tyr 5	-	insertion
Pro 6	-	insertion
Tyr 7	-	insertion
Asp 8	-	insertion
Val 9	-	insertion
Pro 10	-	insertion
Asp 11	-	insertion
Tyr 12	-	insertion
Ala 13	-	insertion
Ser 14	-	insertion
Ala 15	-	insertion
Trp 16	-	insertion
Ser 17	-	insertion
His 18	-	insertion
Pro 19	-	insertion
Gln 20	-	insertion
Phe 21	-	insertion
Glu 22	-	insertion
Lys 23	-	insertion
Gly 24	-	insertion
Gly 25	-	insertion
Ser 26	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	326316.2
Branched	Number of molecules	10
	Total formula weight	4244.0
Non-Polymers*	Number of molecules	12
	Total formula weight	2821.4
All*	Total formula weight	333381.6

*Water molecules are not included.