36OM
Crystal structure of KRAS G13C complexed with GMPPNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 2B of GTPase KRas | polymer | 170 | 19404.9 | 1 | UniProt (P01116) | Homo sapiens (human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D, E, F, G (A) | COBALT (II) ION | non-polymer | 58.9 | 4 | Chemie (CO) PubChem (104729) | |||
| 5 | H (A) | water | water | 18.0 | 136 | Chemie (HOH) |
Sequence modifications
A: 1 - 169 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Cys 13 | Gly 13 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19404.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 782.2 | |
| All* | Total formula weight | 20187.2 |
